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Saturday, September 17, 2011

Physiology of acid secretion:

The parietal cell in the stomach contain receptors for acetylcholine(M3), gastrin(CCK-B), and histamine(H2). There are also cells present near the gastric parietal cells called Enterochromaffin like cells (ECL) which contain receptors for acetylcholine and gastrin.

There are three kinds of acid peptic diseases:

1. Peptic ulcer disease(both gastric and duodenal)
2. Gastroesophageal reflux disease
3. Stress related mucosal injury

Before we discuss how these diseases occur, let's look at the related aggresive and defensive factor associated.