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Friday, November 25, 2016

Alzheimer’s disease is a progressive irreversible neurodegenerative disease of the brain which mainly affects people over 65 years of age. It is the number one cause of dementia. It most commonly presents with the symptoms of memory loss (initially short-term memory loss).

Current treatment option for Alzheimer’s include drugs which increase the acetylcholine level in the brain and decrease the neuronal excitotoxicity. Family support or nursing care is vital in the treatment and it is essential that the caregiver knows about the disease and can adequately care for the person with Alzheimer’s disease.

The main goal of current treatment regimen is to slow down the rate of progression of the disease and improve the memory impairment. Although such measures are only temporary they play a vital role in the quality of life of a person who is suffering from Alzheimer’s disease.

At present no approved treatment is available which targets the disease pathology which means at present there is no cure for the disease. However, scientists are constantly on the lookout for new drugs which can affect the disease pathology, possibly reversing it or curing the patient. But why couldn’t we find a cure for Alzheimer’s disease yet? To understand the answer to this question it is important to have some knowledge about the basic pathology of the disease. Let’s cover some basic background information on Alzheimer’s first.