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Saturday, January 28, 2012

Treatment of ACID PEPTIC Disease

Treatment of acid peptic disease:
What is Acid Peptic disease?

It's a disease of the gastrointestinal tract that is caused by an imbalance between the gastric hydrochloric acid and the protective mucous layer of the gastrointestinal tract.

Acid peptic disease, if untreated could be fatal due to erosion of gastrointestinal tract, leading to tissue damage, rupture of blood vessels and many more complications. But it is very much treatable and can be controlled effectively with mordern medication with very few side effects!

Basically there are 4 major things to consider when treating a patient of peptic ulcer disease"

1. Suppression of gastric acid
2. Enhancement of gastric mucosa
3. Chemical neutralization of the secreted acid and pepsin
4. Eradication of h. pylori
The type of drugs commonly used in the treatment of acid peptic disease are:

1. Drugs that reduce intragastric acidity
2. Drugs that enhance mucosal defense
3. Anti-microbial drugs to destroy H. pylori

Commonly used drugs to reduc intragastric acidity?
1. Antacids
2. H2 receptor antagonists(blocker)
3. Proton pump inhibitors

Commonly used drugs to enhace the gastirc mucous layer:

1. Sucralfate
2. Prostaglandin Analog
3. Bismuth compounds

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