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Monday, October 10, 2011

Aspirin: Basic Mechanism of action of aspirin

Aspirin is a non-selective, non-competetive irrversible cycloxygenase (COX) enzyme inhibitor. Even so it is about 160 times more specific to COX 1 than COX 2. 

The COX enzymes are responsible for the systhesis of prostaglandins (PG) which are the mediators of inflammation, pain, fever, platelet aggregation. 

So aspirin acts by inhibiting the prostaglandin synthesis.

mechanism of action of aspirin
Mechanism of action of aspirin

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