In reality aplasia of the bone marrow is absent and hypoplasia occurs.
Classification of aplastic anaemia:
1. Primary or Idiopathic: No cause is known
a. Drug idiosyncracy
-Cytotoxic drugs-most common
b. Chemical exposure:
c. Viral hepatitis
d. Ionizing radiation
e. Pure red cell aplasia
3. Constitutional –associated with inherited defects in DNA repair eg Fanconi’s syndrome.
What is drug idiosyncracy?
Abnormal reaction to a drug which cause various clinical manifestations.
Reference : In the making of the above article the follwing books were used: