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Saturday, October 1, 2011

Diarrhea: Composition of ORS, Why ORS is effective in diarrhea


Composition of ORS:

The fluid lost in diarrhea is isotonic, so both water and electrolytes need to be replaced. Absorption of electrolytes from the gut is an active process (glucose coupled sodium transport: secondary active transport process) that requires energy. Infected mucosa is capable of very rapid fluid and electrolyte absorption if carbohydrate is available as an energy source. So this is why ORS is effective as it contains glucose as the energy source along with water and electrolytes.




 

Note: Need ORS packet? Clik here to know how to make one or
Click the link to buy Adventure Medical Oral Rehydration Salts (ORS) from Amazon.





The WHO/UNICEF recommended ORS formulation is in 1 liter of water. This means you have to dissolve one packet of ORS in 1 liter of water.

Composition of ORS in Grams/l:

Ingredients
Grams/l
Sodium chloride
3.5
Tri-sodium citrate
2.9
Potassium chloride
1.5
Anhydrous glucose
20



Composition of ORS in Mmol/l:

Ingredient
Mmol/l
Na+
90
K+
20
Cl-
80
Citrate
10
Glucose
111

Note: In the making of the above article, following books were used:




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